Contributes to the daily activities of the Protein Analysis Team, utilizing basic workflows for protein characterization.
Operate, maintain, and troubleshoot LC-MS instrumentation to ensure optimal system performance.
Design, optimize, develop, validate and execute analytical methods (LC-MS, SEC-HPLC, IEX-HPLC, RP-HPLC, and others) for the characterization of therapeutic proteins.
Plan, perform, and document analytical and comparability studies of biologics in accordance with ICH guidelines, applying orthogonal analytical approaches where appropriate.
Prepare protein samples following established protocols, ensuring accuracy and reproducibility.
Apply common proteomic assays and mass spectrometry-related laboratory techniques to support project objectives.
Analyze and interpret complex datasets, preparing clear and comprehensive technical reports.
Collaborate cross-functionally with project teams to support timely and high-quality project delivery.
Wymagania
MSC/Ph.D. degree in life sciences: biochemistry, biotechnology, chemistry, pharmacy, or related fields.
Strong theoretical understanding of protein structure and characterization, including PTMs, higher-order structure, stability, and aggregation.
Practical knowledge of sample preparation for various chromatographic and mass spectrometry-based workflows.
Theoretical knowledge of analytical separation techniques.
Knowledge of methods development and validation in the protein area is in plus.
Familiarity with set-up and data acquisition for global and targeted mass spectrometry approaches is in plus.
Fluency in English, both written and spoken.
High motivation with excellent organization and planning skills.
Communication and team working skills.
Strong desire to work in a challenging and hands-on environment.
Oferujemy
Working in world-class extensive research facilities and modern laboratories.
Daily cooperation and know-how exchange with scientific experts.
Additional benefits: a prepaid lunch card, private medical care, subsidized sports card, and office fruit provision.
Internal Development initiatives including soft & leadership skills training programs.